Can You Take Aspirin with oxycodone

Safety and Interactions of Aspirin and Oxycodon While it is generally safe to take oxycodone and aspirin together under a doctor's guidance, combining these medications should always be done with caution and professional medical oversight. Aspirin (acetylsalicylic acid) is a nonsteroidal anti-inflammatory drug (NSAID) and a common over-the-counter pain reliever, fever reducer, and anti-platelet agent. Oxycodone is a powerful prescription opioid used to treat moderate to severe pain. It is often combined with non-opioid pain relievers (like acetaminophen, which is not aspirin) in combination prescription drugs.
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