2 ketoglutaric acid

Description
2 ketoglutaric acid is a reversible inhibitor of tyrosinase, with an IC50 value of 15 ± 0.5mM[1]. 2-Ketoglutaric acid is naturally found in organisms and is an intermediate in the production of ATP or GTP in the Krebs cycle[2]. Widely used as an antioxidant, 2-Ketoglutaric acid reduced cyanide-induced GSH depletion and DNA damage in rat in vitro and in vivo models[3].
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