Acetosyringone

Description
Acetosyringone is a phenolic compound secreted by plant wounded tissues and is a specific agonist of the VirA/VirG two-component system[1]. Acetosyringone induces the activation of the VirA gene in Agrobacterium tumefaciens, triggering the autophosphorylation of VirA and the subsequent transfer of the phosphate group to the response regulator VirG. The phosphorylated VirG then activates the expression of all virulence (vir) genes on the Ti plasmid, thereby driving the processing, transfer, and stable integration of T-DNA into the plant genome[2]. Acetosyringone is widely used in Agrobacterium-mediated genetic transformation and plant antibacterial mechanism studies[3][4].
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