The Economic Impact of Oxycodone and the Opioid Market

Oxycodone is available in immediate-release and extended-release formulations and may also be combined with other analgesic medicines. The commercial market includes branded and generic products, with generic competition influencing prices and accessibility.

Recent U.S. data demonstrate the importance of Oxycodone within prescription opioid spending. During 2021–2022, adults in the United States accounted for approximately $3.5 billion in average annual outpatient prescription opioid expenditures. Oxycodone alone accounted for approximately $1.9 billion, making it the largest contributor among the major prescription opioids examined in the analysis. There were approximately 19.2 million oxycodone prescription fills during this period.

These figures illustrate that oxycodone has substantial economic value as a pharmaceutical product. Its market supports manufacturers, wholesalers, pharmacies, healthcare professionals, and other parts of the healthcare supply chain. However, the economic value of prescription sales represents only one side of the overall picture.
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