Monsanto Company is a publicly traded American multinational agrochemical and agricultural biotechnology corporation headquartered in Creve Coeur, Greater St. Louis, Missouri. It is a leading producer of genetically engineered (GE) seed and Roundup, a glyphosate-based herbicide. Monsanto's role in agricultural changes, biotechnology products, lobbying of government agencies, and history as a chemical company have made the company controversial.Founded in 1901 by John Francis Queeny, Monsanto initially produced food additives like saccharin and vanillin, expanded into industrial chemicals like sulfuric acid and PCBs in the 1920s, and by the 1940s was a major producer of plastics, including polystyrene and synthetic fibers. Notable achievements by Monsanto and its scientists as a chemical company included breakthrough research on catalytic asymmetric hydrogenation and being the first company to mass-produce light emitting diodes (LEDs). The company also formerly manufactured controversial products such as the insecticide DDT, PCBs, Agent Orange, and recombinant bovine somatotropin (a.k.a. bovine growth hormone).